
Cooling Agent WS-23 is one of the widely used physiological cooling agents for modern food, beverage, confectionery, oral care and personal care formulations. Compared with traditional menthol-based cooling systems, WS-23 is valued for its clean cooling sensation and relatively low flavor interference, making it suitable for formulations where a refreshing effect is required without introducing a strong mint taste.
1.What Is Cooling Agent WS-23?
WS-23 belongs to the WS series of cooling agents and is chemically different from menthol. It is supplied in the form of a white crystalline powder and is commonly used to create a clean, refreshing cooling sensation in finished products. The detail information as follows:
Chemical Name:N,2,3-Trimethyl-2-isopropylbutanamide
CAS NO.:51115-67-4
Appearance: White Powder
Purity:99.9%
Melting Point:Approx. 60–63°C
2.How Does WS-23 Create a Cooling Sensation?
Unlike menthol, WS-23 does not rely primarily on a traditional mint flavor to create the perception of freshness.
WS-23 is a physiological cooling compound that interacts with sensory cold receptors, particularly the TRPM8 pathway. The resulting sensory perception is a cooling or refreshing sensation.
This makes WS-23 especially interesting for product developers who want to separate:
Flavor profile + Cooling sensation
Instead of making a product taste strongly minty in order to create a cooling sensation, formulators can use WS-23 as a dedicated cooling component and use a separate flavor system to create the desired taste.
3.Suggested Starting Dosage
Approximately 50–300 mg/kg (0.005–0.03%) for Confectionery
Approximately 50–300 mg/kg for Chewing Gum
Approximately 10–100 mg/kg (0.001–0.01%) for Beverages
Approximately 0.05–0.25% for Toothpaste and Oral Care Products
Approximately 0.05–0.30% for Cosmetics and Personal Care
4.How to Use WS-23 in Formulations?

5.Why Choose WS-23 for Modern Product Formulation?
High Cooling Efficiency
WS-23 provides noticeable cooling at relatively low dosage levels.
Clean Sensory Profile
It can provide cooling without making the entire formulation strongly mint-flavored.
Broad Application Potential
It can be evaluated in confectionery, beverages, oral care, cosmetics and personal-care products.
Good Flavor Compatibility
WS-23 can be combined with fruit, mint, citrus and other flavor systems.
Easy Formulation Development
It can be pre-dissolved in suitable carriers or incorporated into flavor concentrates before being added to the final product.
Suitable For B2B Ingredient Supply
WS-23 can be supplied in bulk packaging for industrial formulation and product development.